| Id: | 13580
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| Author: | Godal, Tore; Negassi, Kesete
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| Title: | Subclinical infection in leprosy
..-
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| Source: | s.l; s.n; September 15, 1973. 3 p. tab.
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| Abstract: | Lymphocyte transformation has been used to study the immune response to Mycobacterium leprae aomng contacts and non-contacts of leprosy patients. Of 26 subjects living a leprosy endemic area for less than two months none responded to M. leprae; 24% of subjects who had lived in an endemic area for more than a year gave a positive response to M. leprae; more than 50% of individuals with occupational contact of leprosy for more than a year responded; and about 50% of caontacts of tuberculoid and treated lepromatous patients responded to M. leprae, while only 22% (4/18) of contacts of leproamtous patients treated for less than six months responded. It seems that leprosy is more highly infectious than is indicated by the prevalence of the disease and that a subclinical infection commonly follows exposure to M. leprae. The relatively low response found in contacts of active lepromatous patients suggests that in these contacts "superexposure" to M. leprae can bring about a decrease in host resistance.(AU).
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| Descriptors: | TRANSFORMACAO LINFOCITICA
ETIOPIA
HABITACAO
IMUNIDADE
HANSENIASE/genet
HANSENIASE/imunol
HANSENIASE/microbiol
MYCOBACTERIUM BOVIS/imunol
MYCOBACTERIUM LEPRAE/imunol
- FATORES DE TEMPO
DOENCAS OCUPACIONAIS
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| Limits: | HUMANO
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| Electronic Medium: | http://www.ilsl.br
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| Location: | BR191.1; 00624 |
